Prosthetic endocarditis after endoscopic variceal sclerotherapy: a failure of antibiotic prophylaxis

Am J Gastroenterol. 1989 Mar;84(3):311-2.


Bacteremia after esophagogastroduodenoscopy and endoscopic procedures such as esophageal variceal sclerotherapy is well recognized. The theoretical risk of endocarditis has led the American Heart Association and other authorities to recommend antibiotic prophylaxis for these procedures. However, no well-documented episodes of endocarditis associated with endoscopy have been reported. The current case of prosthetic valvular endocarditis is clearly linked to endoscopic sclerotherapy and occurred despite such antibiotic administration. This failure of prophylaxis may be due to factors specific to this patient; however, the efficacy of prophylaxis remains to be proven.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use*
  • Blood Vessel Prosthesis*
  • Endocarditis, Bacterial / etiology*
  • Esophageal and Gastric Varices / therapy*
  • Esophagoscopy / adverse effects*
  • Humans
  • Male
  • Premedication*
  • Sclerosing Solutions / therapeutic use*
  • Sepsis / etiology


  • Anti-Bacterial Agents
  • Sclerosing Solutions