1 Emmert Roberts, MRC Clinical Research Fellow, National Addiction Centre and Department of Psychological Medicine, King's College London, London, UK; Andrea Cipriani, Consultant Psychiatrist, Associate Professor, Department of Psychiatry, University of Oxford, Oxford, UK; John R. Geddes, Professor of Epidemiological Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Oxford, UK; Andrew A. Nierenberg, Director, Dauten Family Center for Bipolar Treatment and Innovation, Massachusetts General Hospital, Boston, Massachusetts, USA; Allan H. Young, Consultant Psychiatrist, King's College London, London, UK. Email: Emmert.roberts@googlemail.com.