Impact of Ethylene Glycol Toxicity on Donor Organ Viability: A Case Report

N L Mendelson; A Fitzgerald; A Kumar; J A Pineda; J MacDougall; R J Solomon; P C Gibson; M Prikis; C E Marroquin

doi:10.1016/j.transproceed.2017.09.004

Impact of Ethylene Glycol Toxicity on Donor Organ Viability: A Case Report

Transplant Proc. 2017 Dec;49(10):2411-2414. doi: 10.1016/j.transproceed.2017.09.004.

Authors

N L Mendelson¹, A Fitzgerald², A Kumar², J A Pineda³, J MacDougall³, R J Solomon², P C Gibson⁴, M Prikis², C E Marroquin⁵

Affiliations

¹ Larner College of Medicine, University of Vermont, Burlington, Vermont.
² Larner College of Medicine, University of Vermont, Burlington, Vermont; Department of Medicine, University of Vermont Medical Center, Burlington, Vermont.
³ Larner College of Medicine, University of Vermont, Burlington, Vermont; Department of Surgery, University of Vermont Medical Center, Burlington, Vermont.
⁴ Larner College of Medicine, University of Vermont, Burlington, Vermont; Department of Pathology, University of Vermont Medical Center, Burlington, Vermont.
⁵ Larner College of Medicine, University of Vermont, Burlington, Vermont; Department of Surgery, University of Vermont Medical Center, Burlington, Vermont. Electronic address: carlos.marroquin@uvmhealth.org.

PMID: 29198693
DOI: 10.1016/j.transproceed.2017.09.004

Abstract

Using kidneys from deceased donors whose demise was secondary to ethylene glycol (EG) toxicity requires considerable thought and planning. The exact impact that kidneys from these donors could have is unclear. The shortage of viable organs and growing wait list mortality should lead us to consider these allografts as potential life-saving transplants. Because it is crucial for the transplant community to use every available allograft, we need to develop processes that optimize each possible scenario. This article is a discussion of the viability of kidneys from a donor with EG-induced brain death and a proposed algorithm for encouraging the use of renal allografts after EG toxicity.

Publication types

Case Reports

MeSH terms

Aged
Ethylene Glycol / poisoning*
Graft Survival / drug effects*
Humans
Kidney Transplantation / methods*
Kidney Transplantation / mortality
Male
Middle Aged
Tissue Donors / supply & distribution*
Tissue and Organ Procurement / methods
Transplantation, Homologous / methods
Transplants / drug effects*
Transplants / supply & distribution

Substances

Ethylene Glycol