Low-intensity LED therapy (658 nm) on burn healing: a series of cases

Lasers Med Sci. 2018 May;33(4):729-735. doi: 10.1007/s10103-017-2399-z. Epub 2017 Dec 4.


The objective of this study was to evaluate the effects of LED on burns healing. Five patients with skin burns were submitted to photobiomodulation by LED, GaAsIP diode, (λ 658 nm) with 40 mW, 7 J/cm2 on every other day. Biopsies of burned skin were performed and the healing process was photographed. Patients with bilateral burns were used as self-control, having one limb being irradiated and the contralateral limb irradiated with placebo. The burns treated with LED showed higher epithelization, with keratinocytes and fibroblasts proliferation, increased collagen synthesis, decreased pain, and pruritus. In conclusion, there was a faster clinical improvement in the irradiated limbs.

Keywords: Burns; Low-intensity LED therapy; Wound healing.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Biopsy
  • Burns / pathology*
  • Burns / radiotherapy*
  • Female
  • Humans
  • Low-Level Light Therapy / methods*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Wound Healing / radiation effects*