Pediatric GIST presenting as anemia

Pediatr Hematol Oncol. 2017 Aug;34(5):343-347. doi: 10.1080/08880018.2017.1396387. Epub 2017 Dec 4.

Abstract

Gastrointestinal stromal tumors (GIST) are tumors of the gastrointestinal (GI) tract originating from the myenteric ganglion cells (interstitial cells of Cajal), that are very rare in children and adolescents. The most common clinical manifestation is acute or chronic, overt or occult GI bleeding although these tumors are asymptomatic in 10-30% of patients. We report a case of gastric GIST in a 11-year-old girl presenting with an iron deficiency refractory anemia without gastrointestinal symptoms and stool evidence of GI bleeding that caused a slight diagnostic delay.

Keywords: Anemia; GIST; children; fecal blood; gastrointestinal stromal tumor.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Iron-Deficiency / diagnosis*
  • Child
  • Female
  • Gastrointestinal Hemorrhage / diagnosis*
  • Gastrointestinal Neoplasms / diagnosis*
  • Humans