Central nervous system vasculitis in Behçet's syndrome: angiographic improvement after therapy with cytotoxic agents

Arthritis Rheum. 1989 Feb;32(2):217-20. doi: 10.1002/anr.1780320217.


We describe a patient with Behçet's syndrome who had clinical and angiographic features of widespread cerebral angiitis of small- and medium-caliber vessels. We report the successful treatment of this condition with a combination of cytotoxic agents and steroids, and demonstrate angiographically the resolution of these abnormalities in neuro-Behçet's disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Behcet Syndrome / complications*
  • Cerebral Angiography
  • Cerebrovascular Disorders / diagnostic imaging
  • Cerebrovascular Disorders / drug therapy
  • Cerebrovascular Disorders / etiology*
  • Chlorambucil / therapeutic use
  • Female
  • Humans
  • Mechlorethamine / therapeutic use
  • Prednisone / therapeutic use


  • Antineoplastic Agents
  • Chlorambucil
  • Mechlorethamine
  • Prednisone