[New international guidelines for curative treatment and prophylaxis for venous thromboembolism (VTE) in cancer patients and the dedicated smartphone application]

J Med Vasc. 2017 Dec;42(6):375-383. doi: 10.1016/j.jdmv.2017.09.006. Epub 2017 Nov 15.
[Article in French]


Venous thromboembolism (VTE) is a frequent and serious complication in cancer patients, and the second leading cause of death in this setting. Cancer patients are also more likely to present recurrent VTE and major bleeding while taking anticoagulants. Management of VTE in these patients is always challenging and remains suboptimal worldwide. In 2013, the International Initiative on Thrombosis and Cancer (ITAC-CME) released international guidelines for the treatment and prophylaxis of VTE and central venous catheter-associated thrombosis, based on a systematic review of the literature ranked according to the Grading of Recommendations Assessment, Development, and Evaluation scale. An update of these ITAC-CME consensus guidelines, including the use of direct oral anticoagulants, was recently published. In this review, we summarize these updated guidelines. Better adherence to the international guidelines, involving an adequate educational and active implementation strategies, will substantially decrease the burden of VTE and allow to increase survival in cancer patients.

Keywords: Cancer; Guidelines; Héparines de bas poids moléculaire; Low-molecular-weight heparins; Maladie thromboembolique veineuse; Recommandations; Traitement; Treatment; Venous thromboembolism.

Publication types

  • Review

MeSH terms

  • Humans
  • Internationality
  • Neoplasms / complications*
  • Practice Guidelines as Topic
  • Smartphone*
  • Venous Thromboembolism / etiology*
  • Venous Thromboembolism / prevention & control
  • Venous Thromboembolism / therapy*