Complement activation after prolonged exercise

Clin Chim Acta. 1989 Jan 13;179(1):45-9. doi: 10.1016/0009-8981(89)90021-1.


The effects of a 2.5-h running test on the concentrations of the complement cleavage products C3a, C4a and C5a in plasma were examined in eight healthy young males. In all participants the C3a and C4a values were raised during (1 h after the start) and immediately after exercise. C4a was also raised 1 and 3 h after the race. These results provide evidence for complement activation after prolonged exercise.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Complement Activation*
  • Exercise*
  • Humans
  • Male