Quinoxaline: An insight into the recent pharmacological advances

Abstract

Quinoxaline, a fused heterocycle of benzene and pyrazine rings has gained considerable attention in the field of contemporary medicinal chemistry. The moiety is of substantial importance because of its wide array of pharmacological activities viz. anti-cancer, antimalarial, anti-inflammatory, antimicrobial, anti-HIV etc. Diversely substituted quinoxalines are important therapeutic agents in the pharmaceutical industry. This review focusses on the quinoxaline derivatives developed during the last decennial period and their biomedical applications. A compilation of patents on quinoxaline is also included herein.

Keywords: Anti-cancer; Anti-inflammatory; Antimalarial; Antimicrobial; Biological applications; Quinoxaline.