Effects of subgingival irrigation on A. actinomycetemcomitans

J Clin Periodontol. 1989 Feb;16(2):116-9. doi: 10.1111/j.1600-051x.1989.tb01623.x.


The effects of repeated subgingival irrigation on Actinobacillus actinomycetemcomitans was examined. 24 periodontal pockets harboring A. actinomycetemcomitans in 3 juvenile and 4 adult periodontitis patients were studied. The protocol included bi-weekly subgingival irrigation with hydrogen peroxide of the periodontal sites until the micro-organism was no longer detected by selective culture, or for 6 months. A. actinomycetemcomitans was gradually suppressed to below detection following the irrigation regime and could no longer be detected in 46% of the sites at completion of the irrigation protocol. The sites were microbiologically re-examined 5 months after cessation of the irrigation regime. A. actinomycetemcomitans re-occurred in only 2 of the sites from which it had originally been suppressed below detection. The results indicate: (1) that the irrigation regime tested has some potential to suppress A. actinomycetemcomitans in periodontal pockets; (2) that the effect of the irrigation protocol generally lasted for 5 months; (3) that the reduction rate of A. actinomycetemcomitans to below detectable levels seems related to the initial number of cultivable bacteria from the periodontal pocket.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Actinobacillus / drug effects
  • Actinobacillus / isolation & purification*
  • Adolescent
  • Adult
  • Aggressive Periodontitis / microbiology
  • Aggressive Periodontitis / therapy*
  • Dental Plaque / microbiology
  • Dental Plaque / therapy
  • Female
  • Gingiva / microbiology
  • Humans
  • Hydrogen Peroxide / administration & dosage
  • Hydrogen Peroxide / therapeutic use*
  • Male
  • Middle Aged
  • Periodontal Diseases / therapy*
  • Periodontal Pocket / microbiology*
  • Periodontitis / microbiology*
  • Periodontitis / therapy*
  • Therapeutic Irrigation / methods*


  • Hydrogen Peroxide