Challenges and recommendations for epigenomics in precision health
Nat Biotechnol
.
2017 Dec 8;35(12):1128-1132.
doi: 10.1038/nbt.4030.
Authors
Ava C Carter
1
,
Howard Y Chang
1
,
George Church
2
,
Ashley Dombkowski
3
,
Joseph R Ecker
4
,
Elad Gil
5
,
Paul G Giresi
6
,
Henry Greely
7
,
William J Greenleaf
1
8
,
Nir Hacohen
9
,
Chuan He
10
,
David Hill
11
,
Justin Ko
12
,
Isaac Kohane
13
,
Anshul Kundaje
14
,
Megan Palmer
15
,
Michael P Snyder
1
8
,
Joyce Tung
16
,
Alexander Urban
1
17
,
Marc Vidal
11
,
Wing Wong
1
18
Affiliations
1
Center for Personal Dynamic Regulomes, Stanford University, Stanford, California, USA.
2
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA, and Wyss Institute, Boston, Massachusetts, USA.
3
BEFORE Brands, Menlo Park, California, USA.
4
The Salk Institute for Biological Studies, La Jolla, California, USA, and Howard Hughes Medical Institute.
5
Color Genomics, Burlingame, California, USA.
6
Epinomics, Menlo Park, California, USA.
7
Center for Law and the Biosciences, Stanford University, Stanford, California, USA.
8
Department of Genetics, Stanford University, Stanford, California, USA.
9
Massachusetts General Hospital, Boston, Massachusetts, USA.
10
University of Chicago, Chicago, Illinois, USA, & Howard Hughes Medical Institute.
11
Center for Cancer Systems Biology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
12
Department of Dermatology, Stanford University, Stanford, California, USA.
13
Department of Medical Informatics, Harvard Medical School, Boston, Massachusetts, USA.
14
Departments of Genetics and Computer Science, Stanford University, Stanford, California, USA.
15
Center for International Security and Cooperation, Stanford University, Stanford, California, USA.
16
23andMe, Mountain View, California, USA.
17
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
18
Department of Statistics, Stanford University, Stanford, California, USA.
PMID:
29220033
PMCID:
PMC5821229
DOI:
10.1038/nbt.4030
No abstract available
Publication types
Research Support, Non-U.S. Gov't
MeSH terms
Epigenomics*
Humans
Information Dissemination
Precision Medicine*
Grants and funding
RM1 HG008935/HG/NHGRI NIH HHS/United States
P50 HG005550/HG/NHGRI NIH HHS/United States
RM1 HG008525/HG/NHGRI NIH HHS/United States
P50 HG004233/HG/NHGRI NIH HHS/United States
P50 HG007735/HG/NHGRI NIH HHS/United States
R01 HG007834/HG/NHGRI NIH HHS/United States
P50 MH106933/MH/NIMH NIH HHS/United States
P50 HG002357/HG/NHGRI NIH HHS/United States