iPSC Reprogramming Is Not Just an Open and Shut Case

Cell Stem Cell. 2017 Dec 7;21(6):711-712. doi: 10.1016/j.stem.2017.11.017.


What exactly happens to chromatin as cells undergo an identity change? In this issue of Cell Stem Cell, Li et al. (2017) and Knaupp et al. (2017) offer new insights by mapping in exquisite detail chromatin accessibility dynamics as mouse embryonic fibroblasts are reprogrammed into induced pluripotent stem cells.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cellular Reprogramming
  • Chromatin
  • Fibroblasts
  • Induced Pluripotent Stem Cells*
  • Mice


  • Chromatin