Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Feb;21(1):23-30.
doi: 10.1136/eb-2017-102760. Epub 2017 Dec 9.

Heart rate variability in bipolar disorder and borderline personality disorder: a clinical review

Affiliations
Review

Heart rate variability in bipolar disorder and borderline personality disorder: a clinical review

Oliver Carr et al. Evid Based Ment Health. 2018 Feb.

Abstract

Heart rate variability (HRV) in psychiatric disorders has become an increasing area of interest in recent years following technological advances that enable non-invasive monitoring of autonomic nervous system regulation. However, the clinical interpretation of HRV features remain widely debated or unknown. Standardisation within studies of HRV in psychiatric disorders is poor, making it difficult to reproduce or build on previous work. Recently, a Guidelines for Reporting Articles on Psychiatry and Heart rate variability checklist has been proposed to address this issue. Here we assess studies of HRV in bipolar disorder and borderline personality disorder against this checklist and discuss the implication for ongoing research in this area.

Keywords: cardiology; depression & mood disorders; pacing & electrophysiology; personality disorders; psychiatry.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) An ECG signal with R peaks denoted by black dots. (B) The corresponding tachogram or R–R interval series.

Similar articles

Cited by

References

    1. Alvares GA, Quintana DS, Hickie IB, et al. . Autonomic nervous system dysfunction in psychiatric disorders and the impact of psychotropic medications: a systematic review and meta-analysis. J Psychiatry Neurosci 2016;41:89–104. 10.1503/jpn.140217 - DOI - PMC - PubMed
    1. Quintana DS, Guastella AJ, Outhred T, et al. . Heart rate variability is associated with emotion recognition: direct evidence for a relationship between the autonomic nervous system and social cognition. Int J Psychophysiol 2012;86:168–72. 10.1016/j.ijpsycho.2012.08.012 - DOI - PubMed
    1. Hansen AL, Johnsen BH, Sollers JJ, et al. . Heart rate variability and its relation to prefrontal cognitive function: the effects of training and detraining. Eur J Appl Physiol 2004;93:263–72. 10.1007/s00421-004-1208-0 - DOI - PubMed
    1. Reinecke A, Filippini N, Berna C, et al. . Effective emotion regulation strategies improve fMRI and ECG markers of psychopathology in panic disorder: implications for psychological treatment action. Transl Psychiatry 2015;5:e673–10. 10.1038/tp.2015.160 - DOI - PMC - PubMed
    1. Malpas SC. Neural influences on cardiovascular variability: possibilities and pitfalls. Am J Physiol Heart Circ Physiol 2002;282:H6–20. - PubMed

Publication types

MeSH terms