Cellulite: a review of pathogenesis-directed therapy

Semin Cutan Med Surg. 2017 Dec;36(4):179-184. doi: 10.12788/j.sder.2017.031.


Cellulite is a condition that affects the majority of postpubertal women and can negatively impact quality of life. This review discusses several proposed pathophysiologies of cellulite, and examines treatment options that have been utilized, focusing on the etiologic factor targeted by the therapies. This approach aims to help clarify the pathogenesis of cellulite and provide a road map for developing effective treatment paradigms for patients.

Publication types

  • Review

MeSH terms

  • Cellulite / etiology
  • Cellulite / pathology
  • Cellulite / physiopathology*
  • Cellulite / therapy*
  • Collagen / physiology
  • Cosmetic Techniques*
  • Edema / pathology
  • Female
  • Humans
  • Male
  • Microcirculation
  • Protein Denaturation
  • Quality of Life
  • Skin / physiopathology
  • Subcutaneous Fat / pathology


  • Collagen