Tyrosine kinase inhibitor and rituximab-CHOP treatment for concurrent chronic myeloid leukemia and non-Hodgkin lymphoma: a case report

Clin Case Rep. 2017 Nov 2;5(12):2047-2050. doi: 10.1002/ccr3.1253. eCollection 2017 Dec.

Abstract

Non-Hodgkin lymphoma can occur concurrently with chronic phase-chronic myeloid leukemia (CML) at initial diagnosis. Combination treatment with second-generation tyrosine kinase inhibitors and rituximab-CHOP for patients newly diagnosed with CML and non-Hodgkin lymphoma is effective for both diseases. However, we found that this treatment combination may induce severe myelosuppression.

Keywords: Chronic myeloid leukemia; myelosuppression; non‐Hodgkin lymphoma; primary mediastinal large B‐cell lymphoma; tyrosine kinase inhibitor.

Publication types

  • Case Reports