Natural Products and HIV/AIDS

AIDS Res Hum Retroviruses. 2018 Jan;34(1):31-38. doi: 10.1089/AID.2017.0232. Epub 2018 Jan 10.

Abstract

The study of natural products in biomedical research is not a modern concept. Many of the most successful medical therapeutics are derived from natural products, including those studied in the field of HIV/AIDS. Biomedical research has a rich history of discovery based on screens of medicinal herbs and traditional medicine practices. Compounds derived from natural products, which repress HIV and those that activate latent HIV, have been reported. It is important to remember the tradition in medical research to derive therapies based on these natural products and to overcome the negative perception of natural products as an "alternative medicine."

Keywords: AIDS; HIV; HIV reactivation; HIV suppression; natural products.

Publication types

  • Review

MeSH terms

  • Anti-HIV Agents / chemistry
  • Anti-HIV Agents / pharmacology*
  • Biological Products / chemistry
  • Biological Products / pharmacology*
  • HIV Infections / drug therapy
  • HIV-1 / drug effects*
  • HIV-1 / physiology
  • Humans
  • Plants, Medicinal / chemistry
  • Virus Latency / drug effects
  • Virus Replication / drug effects

Substances

  • Anti-HIV Agents
  • Biological Products