Abstract
This review is aimed to provide a concise yet extensive survey of key short bioactive peptide sequences for a range of applications ranging from biomaterials development to peptides with therapeutic uses. The following are considered: cell adhesion motifs, structural peptides, cell-penetrating and tumor-homing peptides, antimicrobial peptides, peptide hormones, growth factors and matrix metalloprotease substrates, neuropeptides, amyloid peptides, antioxidant peptides, peptide affinity tags, anticancer peptides, and others. This review provides a convenient resource, summarizing a broad range of important sequences with great utility as a resource concerning both small peptide drugs and also novel biofunctional peptide-based materials.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amyloid / chemistry
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Amyloid / metabolism
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Antimicrobial Cationic Peptides / chemistry
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Antimicrobial Cationic Peptides / metabolism
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Antimicrobial Cationic Peptides / therapeutic use
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / metabolism
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Antineoplastic Agents / therapeutic use
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Antioxidants / chemistry
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Antioxidants / metabolism
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Antioxidants / therapeutic use
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Biocompatible Materials / chemistry
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Biocompatible Materials / metabolism*
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Biocompatible Materials / therapeutic use
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Cell-Penetrating Peptides / chemistry
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Cell-Penetrating Peptides / metabolism
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Humans
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Peptide Hormones / chemistry
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Peptide Hormones / metabolism
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Peptide Hormones / therapeutic use
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Peptides / chemistry
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Peptides / metabolism*
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Peptides / therapeutic use
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Tissue Engineering
Substances
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Amyloid
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Antimicrobial Cationic Peptides
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Antineoplastic Agents
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Antioxidants
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Biocompatible Materials
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Cell-Penetrating Peptides
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Peptide Hormones
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Peptides