Glut3 Addiction: A Druggable Vulnerability in Glioblastoma

Cancer Cell. 2017 Dec 11;32(6):726-727. doi: 10.1016/j.ccell.2017.11.017.


The link between GBM molecular subtype and response to treatment remains undefined. In this issue of Cancer Cell, Cosset and colleagues define a subpopulation of patients within the proneural/classical subtype sensitive to integrin blockade because of a Glut3 addiction. These findings reveal context-dependent druggable vulnerability in a subpopulation of GBM.

Publication types

  • Comment

MeSH terms

  • Adult
  • Brain Neoplasms*
  • Glioblastoma*
  • Humans