The association between the metabolic syndrome and metabolic syndrome score and pulmonary function in non-smoking adults

Diab Vasc Dis Res. 2018 Mar;15(2):131-138. doi: 10.1177/1479164117746022. Epub 2017 Dec 13.

Abstract

Objective: This study assessed the association of metabolic syndrome and metabolic syndrome score with the predicted forced vital capacity and predicted forced expiratory volume in 1 s (predicted forced expiratory volume in 1 s) values in Korean non-smoking adults.

Methods: We analysed data obtained from 6684 adults during the 2013-2015 Korean National Health and Nutrition Examination Survey.

Results: After adjustment for related variables, metabolic syndrome ( p < 0.001) and metabolic syndrome score ( p < 0.001) were found to be inversely associated with the predicted forced vital capacity and forced expiratory volume in 1 s values. The odds ratios of restrictive pulmonary disease (the predicted forced vital capacity < 80.0% with forced expiratory volume in 1 s/FVC ⩾ 70.0%) by metabolic syndrome score with metabolic syndrome score 0 as a reference group showed no significance for metabolic syndrome score 1 [1.061 (95% confidence interval, 0.755-1.490)] and metabolic syndrome score 2 [1.247 (95% confidence interval, 0.890-1.747)], but showed significant for metabolic syndrome score 3 [1.433 (95% confidence interval, 1.010-2.033)] and metabolic syndrome score ⩾ 4 [1.760 (95% confidence interval, 1.216-2.550)]. In addition, the odds ratio of restrictive pulmonary disease of the metabolic syndrome [1.360 (95% confidence interval, 1.118-1.655)] was significantly higher than those of non-metabolic syndrome.

Conclusion: Metabolic syndrome and metabolic syndrome score were inversely associated with the predicted forced vital capacity and forced expiratory volume in 1 s values in Korean non-smoking adults. In addition, metabolic syndrome and metabolic syndrome score were positively associated with the restrictive pulmonary disease.

Keywords: Metabolic syndrome; metabolic syndrome score; non-smoker; pulmonary function; restrictive pulmonary diseases.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Forced Expiratory Volume / physiology
  • Humans
  • Lung / physiopathology*
  • Male
  • Metabolic Syndrome / complications
  • Metabolic Syndrome / physiopathology*
  • Middle Aged
  • Nutrition Surveys
  • Odds Ratio
  • Respiratory Function Tests
  • Smoking
  • Vital Capacity / physiology*