Diabetic Zucker rat Tibialis anterior muscle high-frequency electrical stimulation (HFES) data: Regulation of MAPKs associated proteins

Gautam K Ginjupalli; Kevin M Rice; Anjaiah Katta; Nandini D P K Manne; Ravikumar Arvapalli; Miaozong Wu; Shinichi Asano; Eric R Blough

doi:10.1016/j.dib.2017.11.030

Diabetic Zucker rat Tibialis anterior muscle high-frequency electrical stimulation (HFES) data: Regulation of MAPKs associated proteins

Data Brief. 2017 Nov 13:16:346-353. doi: 10.1016/j.dib.2017.11.030. eCollection 2018 Feb.

Authors

Gautam K Ginjupalli¹, Kevin M Rice^{1

2

3

4}, Anjaiah Katta¹, Nandini D P K Manne⁵, Ravikumar Arvapalli¹, Miaozong Wu⁶, Shinichi Asano⁷, Eric R Blough^{1

3

8

9}

Affiliations

¹ Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA.
² Department of Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA.
³ Biotechnology Graduate Program West Virginia State University, Institute, WV, USA.
⁴ Department of Health and Human Service, School of Kinesiology, Marshall University, Huntington, WV, USA.
⁵ Department of Public Heath, Marshall University, Huntington, WV, USA.
⁶ College of Health, Science, and Technology, University of Central Missouri, Warrensburg, MO, USA.
⁷ School of Education, Health, and Human Performance, Fairmont State University, Fairmont, WV, USA.
⁸ Department of Pharmaceutical Sciences and Research, School of Pharmacy, Marshall University, Huntington, WV, USA.
⁹ Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA.

Abstract

Anaerobic exercise has been advocated as a prescribed treatment for the management of diabetes: however, alterations in exercise-induced signaling remain largely unexplored in the diabetic muscle. Here, we compare the basal and the in situ contraction-induced phosphorylation of the mitogen-activated protein kinases (MAPKs) ERK 1/2, p38, and JNK in the lean and obese (fa/fa) Zucker rat tibialus anterior (TA) muscle following a single bout of contractile stimuli. This article represents data associated with prior publications from our lab (Katta et al., 2009, Katta et al., 2009, Tullgren et al., 1991) [1-3] and concurrent Data in Brief articles (Ginjupalli et al., 2017, Rice et al., 2017, Rice et al., 2017, Rice et al., 2017) [4-7].

Keywords: Diabetes; High-frequency electrical stimulation (HFES); MAPK; Skeletal muscle; Tibialus anterior; Zucker rat.