[Neuroendocrine tumors of the abdomen]

Radiologe. 2018 Jan;58(1):36-44. doi: 10.1007/s00117-017-0332-x.
[Article in German]

Abstract

Clinical/methodical issue: Gastroenteropancreatic neuroendocrine neoplasia (GEP-NEN) are a heterogeneous group of complex tumors, which is often difficult to classify due to heterogeneity and varying locations.

Standard radiological methods: Ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and positron-emission tomography computed tomography (PET/CT) are available for the localization of NEN as well as for the staging.

Methodological innovations: In particular, nuclear medical examination methods with somatostatin analogues are of great importance since radioactively labeled receptor ligands make tumors visible with high sensitivity.

Performance: CT and MRT have high detection rates for GEP-NEN and have been further improved by developments such as diffusion weighted imaging. The nuclear medical methods, however, are superior in detection, especially in gastrointestinal NEN ACHIEVEMENTS: It is important for the radiologist to become acquainted with the NEN as they can occur ubiquitously in the abdomen and should be identified as such.

Practical recommendations: Since GEP-NEN are predominantly hypervascularized, a biphasic examination technique is obligatory for contrast-enhanced cross-sectional imaging. PET/CT with somatostatin analogs should be used for further diagnosis.

Keywords: Computed tomography; Gastroenteropancreatic neuroendocrine neoplasias; Magnetic resonance imaging; Metastasis; Sensitivity.

Publication types

  • Review

MeSH terms

  • Abdomen*
  • Humans
  • Magnetic Resonance Imaging
  • Neuroendocrine Tumors*
  • Positron Emission Tomography Computed Tomography*
  • Positron-Emission Tomography
  • Tomography, X-Ray Computed