A Novel Porous Diamond - Titanium Biomaterial: Structure, Microstructure, Physico-Mechanical Properties and Biocompatibility

An Acad Bras Cienc. Oct-Dec 2017;89(4):3111-3121. doi: 10.1590/0001-3765201720160750. Epub 2017 Dec 11.

Abstract

With the aim of introducing permanent prostheses with main properties equivalent to cortical human bone, Ti-diamond composites were processed through powder metallurgy. Grade 1 titanium and mixtures of Ti powder with 2%, 5% and 10 wt% diamond were compacted at 100MPa, and then sintered at 1250°C/2hr/10-6mbar. Sintered samples were studied in the point of view of their microstructures, structures, yield strength and elastic modulus. The results showed that the best addition of diamonds was 2 wt%, which led to a uniform porosity, yield strength of 370MPa and elastic modulus of 13.9 GPa. Samples of Ti and Ti-2% diamond were subjected to in vitro cytotoxicity test, using cultures of VERO cells, and it resulted in a biocompatible and nontoxic composite material.

MeSH terms

  • Animals
  • Biocompatible Materials / analysis*
  • Chlorocebus aethiops
  • Diamond / analysis*
  • Humans
  • Materials Testing / methods*
  • Porosity
  • Surface Properties
  • Tensile Strength
  • Titanium / analysis*
  • Vero Cells

Substances

  • Biocompatible Materials
  • Diamond
  • Titanium