Dynamic flow imaging using 320-detector row CT and motion coherence analysis in coronary aneurysms associated with Kawasaki disease

Cardiol Young. 2018 Mar;28(3):416-420. doi: 10.1017/S1047951117002293. Epub 2017 Dec 14.


Introduction We propose a new dynamic flow imaging using 320-detector row CT, and investigate the assessment of coronary flow in aneurysms of Kawasaki disease in adulthood.

Methods: Six patients with Kawasaki disease and coronary aneurysms associated (26.7 years old) and six controls were enrolled. Dynamic coronary CT angiography with 320-row CT was continuously performed at mid-diastole throughout 15-25 cardiac cycles with prospective Electrocardiogram gating after injection of contrast media. Dynamic data sets of 15-25 cycles were computed into 90-100 data sets by motion coherence image processing. Next, time-density curves for coronary arteries were calculated for all the phases. On the basis of the maximum slope method, coronary flow index was defined as the ratio of the maximum upslope of the attenuation of coronary arteries to the upslope of the attenuation of ascending aorta on the time-density curves. Coronary flow indexes for the proximal and distal sites of coronary arteries and intra-aneurysm were measured.

Keywords: CT; Kawasaki disease; coronary artery aneurysm; general cardiology; motion coherence image processing.

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Computed Tomography Angiography
  • Contrast Media / administration & dosage
  • Coronary Aneurysm / diagnostic imaging*
  • Coronary Angiography
  • Coronary Vessels / pathology*
  • Electrocardiography
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Japan
  • Male
  • Mucocutaneous Lymph Node Syndrome / complications*
  • Retrospective Studies
  • Young Adult


  • Contrast Media