GABAergic septohippocampal neurons contain parvalbumin

Brain Res. 1989 Jan 30;478(2):375-81. doi: 10.1016/0006-8993(89)91520-5.


Septal axons were visualized in the hippocampus by anterograde transport of Phaseolus vulgaris leucoagglutinin (PHAL) injected into the medial septal region, which contains large numbers of parvalbumin (PV)-immunoreactive somata. A proportion of the PHAL-labelled afferents in the hippocampus were shown to be immunoreactive for PV by immunostaining alternate sections. This population of septohippocampal axons alone was found to be immunoreactive for gamma-aminobutyric acid (GABA) following post-embedding immunogold staining of ultrathin sections cut from the same material.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Hippocampus / cytology
  • Hippocampus / metabolism*
  • Immunohistochemistry
  • Muscle Proteins / metabolism*
  • Parvalbumins / metabolism*
  • Phytohemagglutinins
  • Rats
  • Rats, Inbred Strains
  • Septal Nuclei / cytology
  • Septal Nuclei / metabolism*
  • gamma-Aminobutyric Acid / metabolism*


  • Muscle Proteins
  • Parvalbumins
  • Phytohemagglutinins
  • gamma-Aminobutyric Acid