Safety Assessment of Plant-Derived Fatty Acid Oils

Int J Toxicol. 2017 Nov/Dec;36(3_suppl):51S-129S. doi: 10.1177/1091581817740569.


The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 244 plant-derived fatty acid oils as used in cosmetics. Oils are used in a wide variety of cosmetic products for their skin conditioning, occlusive, emollient, and moisturizing properties. Since many of these oils are edible, and their systemic toxicity potential is low, the review focused on potential dermal effects. The Panel concluded that the 244 plant-derived fatty acid oils are safe as used in cosmetics.

Keywords: cosmetics; oils; safety.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Consumer Product Safety*
  • Cosmetics / chemistry
  • Cosmetics / toxicity*
  • Emollients / chemistry
  • Emollients / toxicity
  • Fatty Acids / chemistry
  • Fatty Acids / toxicity*
  • Humans
  • Plant Oils / chemistry
  • Plant Oils / toxicity*
  • Toxicity Tests / methods*


  • Cosmetics
  • Emollients
  • Fatty Acids
  • Plant Oils