Two new species of the Liolaemus donosobarrosi clade are described. Liolaemus tirantii sp. nov. and Liolaemus calliston sp. nov. differ from other members of their clade by a combination of coloration characters, morphometric and molecular traits. Liolaemus tirantii sp. nov. is known from three localities separated only a few kilometers from each other and Liolaemus calliston sp. nov. is known only from the type locality. Both species inhabit a region strongly impacted by oil and gas extraction but their conservation status is unknown.
Keywords: Reptilia, Argentina, Liolaemidae, Liolaemus tirantii sp. nov., Liolaemus calliston sp. nov., Liolaemus donosobarrosi clade, Northwestern Patagonia.