A case of liver abscess co-infected with Desulfovibrio desulfuricans and Escherichia coli and review of the literature

J Infect Chemother. 2018 May;24(5):393-397. doi: 10.1016/j.jiac.2017.11.006. Epub 2017 Dec 18.

Abstract

A 73-year-old woman was admitted with consciousness disturbance following a fever. Abdominal computed tomography revealed a large liver abscess with which the presence of Desulfovibrio desulfuricans and Escherichia coli was confirmed by thorough blood and abscess content culture. Empiric meropenem treatment was switched to cefoperazone/sulbactam, followed by ampicillin/sulbactam based on susceptibility testing. Desulfovibrio desulfuricans is a common bacterium that rarely causes liver abscess and may be overlooked during co-infection due to overgrowth of the accompanying bacteria. Clinicians should bear Desulfovibrio desulfuricans in mind and select the appropriate antibiotics according to susceptibility testing when anaerobic bacteria are detected in a liver abscess.

Keywords: Co-infection; Desulfovibrio desulfuricans; Liver abscess.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Ampicillin / administration & dosage
  • Cefoperazone / administration & dosage
  • Coinfection / blood
  • Coinfection / drug therapy
  • Coinfection / microbiology*
  • Desulfovibrio desulfuricans / drug effects
  • Desulfovibrio desulfuricans / isolation & purification*
  • Desulfovibrionaceae Infections / blood
  • Desulfovibrionaceae Infections / drug therapy
  • Desulfovibrionaceae Infections / microbiology*
  • Drug Therapy, Combination
  • Escherichia coli / drug effects
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / blood
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / microbiology*
  • Female
  • Humans
  • Liver Abscess / diagnostic imaging
  • Liver Abscess / drug therapy
  • Liver Abscess / microbiology*
  • Meropenem
  • Thienamycins / administration & dosage

Substances

  • Thienamycins
  • Ampicillin
  • Cefoperazone
  • Meropenem