Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Apr;57(4):1119-25.

Campylobacter Pylori Virulence Factors in Gnotobiotic Piglets

Free PMC article

Campylobacter Pylori Virulence Factors in Gnotobiotic Piglets

K A Eaton et al. Infect Immun. .
Free PMC article


Thirty-three gnotobiotic piglets from four litters were challenged with motile and nonmotile strains of Campylobacter pylori. The most motile strain, 26695, was the most virulent, with a 100% infection rate. The least motile strain, Tx30a, was the least virulent, with an infection rate of only 17%. Strain 60190 was weakly motile and had intermediate virulence, with an infection rate of 40%. Strains recovered from piglets were more motile than the challenge strains. The challenge strains also differed in cytotoxin production. The least virulent strain, Tx30a, was nontoxigenic, while the other two strains produced high levels of cytotoxin. Thus, virulence of C. pylori for gnotobiotic piglets correlated very well with motility and not as well with cytotoxin production.

Similar articles

See all similar articles

Cited by 69 articles

See all "Cited by" articles


    1. Infect Immun. 1975 May;11(5):890-7 - PubMed
    1. J Gen Microbiol. 1988 Jan;134(1):43-52 - PubMed
    1. Infect Immun. 1978 Nov;22(2):387-92 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Jan;76(1):391-5 - PubMed
    1. Infect Immun. 1982 Dec;38(3):1296-8 - PubMed


LinkOut - more resources