Coexistent cardiac tumours and malformations of the heart

Int J Cardiol. 1989 Jan;22(1):89-98. doi: 10.1016/0167-5273(89)90140-x.


Cardiac tumours and anatomical malformations of the heart may produce similar clinical signs and symptoms. The coexistence of these two abnormalities complicates diagnosis and probably adversely affects prognosis. We present a review of four cases of this rare combination. In the first case, Ebstein's malformation was present in a child with tuberous sclerosis and cardiac rhabdomyomata. Right ventricular rhabdomyomata were associated with a hypoplastic tricuspid valve in the second case. In the third case, cardiac myxomas were detected in a child with a double-chambered right ventricle. The fourth case was a child with a fibroma of the right ventricle with pulmonary atresia. We propose that, in some circumstances, a space-occupying lesion may be associated with, or possibly induce, a malformation within the developing heart.

Publication types

  • Case Reports

MeSH terms

  • Ebstein Anomaly / pathology
  • Female
  • Fetal Death / pathology
  • Fibroma / congenital
  • Heart Atria / pathology
  • Heart Defects, Congenital / pathology*
  • Heart Neoplasms / congenital*
  • Heart Neoplasms / pathology
  • Heart Ventricles / pathology
  • Humans
  • Infant, Newborn
  • Male
  • Myxoma / congenital
  • Pregnancy
  • Rhabdomyoma / congenital
  • Tuberous Sclerosis / congenital