LncRNA Seduction of GOT2 Goes Viral

Y Grace Chen; Howard Y Chang

doi:10.1016/j.immuni.2017.12.006

LncRNA Seduction of GOT2 Goes Viral

Immunity. 2017 Dec 19;47(6):1021-1023. doi: 10.1016/j.immuni.2017.12.006.

Authors

Y Grace Chen¹, Howard Y Chang²

Affiliations

¹ Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305.
² Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305. Electronic address: howchang@stanford.edu.

PMID: 29262346
DOI: 10.1016/j.immuni.2017.12.006

Abstract

Mechanisms of viral infection are active areas of investigation. In a recent issue of Science, Wang et al. (2017) reveal an additional function of a host-encoded long non-coding RNA (lncRNA) in regulating viral expression by binding a host metabolic enzyme to enhance its catalytic activity.

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MeSH terms

Antiviral Agents*
Interferons
MicroRNAs*
RNA, Long Noncoding*
Virus Replication

Substances

Antiviral Agents
MicroRNAs
RNA, Long Noncoding
Interferons