Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53

Leukemia. 2018 Mar;32(3):850-854. doi: 10.1038/leu.2017.325. Epub 2017 Nov 16.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Clonal Evolution / genetics*
  • DNA Damage / genetics*
  • Gene Expression*
  • Genetic Association Studies
  • Genotype
  • Hematopoietic Stem Cells / metabolism*
  • Humans
  • Mice
  • Mice, Transgenic
  • Mutation*
  • Phenotype
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Tumor Suppressor Protein p53