Web-based cognitive rehabilitation for survivors of adult cancer: A randomised controlled trial

Psychooncology. 2018 Apr;27(4):1172-1179. doi: 10.1002/pon.4615. Epub 2018 Feb 15.

Abstract

Objective: Cognitive dysfunction associated with cancer is frequently reported and can reduce quality of life. This study evaluated a Web-based cognitive rehabilitation therapy program (eReCog) in cancer survivors compared with a waitlist control group.

Methods: Adult cancer survivors with self-reported cognitive symptoms who had completed primary treatment at least 6 months prior were recruited. Participants completed telephone screening and were randomly allocated to the 4-week online intervention or waitlist. Primary outcome was perceived cognitive impairment assessed with the Functional Assessment of Cancer Therapy-Cognitive Function version 3. Secondary outcomes were additional measures of subjective cognitive functioning, objective cognitive functioning, and psychosocial variables.

Results: Seventy-six women were allocated to the intervention (n = 40) or waitlist (n = 36). A significant interaction was found on the instrumental activities of daily living measure of self-reported prospective memory whereby the intervention group reported a greater reduction in prospective memory failures than the waitlist group. Interaction trends were noted on perceived cognitive impairments (P = .089) and executive functioning (P = .074). No significant interactions were observed on other measures of objective cognitive functioning or psychosocial variables.

Conclusions: The Web-based intervention shows promise for improving self-reported cognitive functioning in adult cancer survivors. Further research is warranted to better understand the mechanisms by which the intervention might contribute to improved self-reported cognition.

Keywords: Web-based; adult; cancer; cognitive rehabilitation; oncology; online; survivors.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Attitude of Health Personnel*
  • Breast Neoplasms / psychology
  • Breast Neoplasms / therapy
  • Cancer Survivors / psychology*
  • Cognition Disorders / psychology*
  • Cognition Disorders / therapy
  • Cognitive Remediation / methods*
  • Executive Function
  • Female
  • Humans
  • Internet*
  • Leukemia / psychology
  • Leukemia / therapy
  • Memory, Episodic
  • Middle Aged
  • Psychiatric Rehabilitation / methods*
  • Social Workers / psychology
  • Sweden
  • Therapy, Computer-Assisted*