Comparison of the plaque microflora in immunodeficient and immunocompetent dental patients

J Dent Res. 1979 Dec;58(12):2344-52. doi: 10.1177/00220345790580120301.


The nature and extent of the immune dysfunctions in 20 immunodeficient patients, as well as the immunocompetence of 22 control subjects, were verified by cell-mediated responsiveness and immunoglobulin quantitations. Comparisons of the microbial composition of supragingival plaque between the two populations showed that a greater number of immunodeficient than control subjects harbored Candida sp. and Staphylococcus sp. Conversely, a lower number of immunodeficient than control subjects harbored Streptococcus mutans. Also, patients with immune dysfunctions had a lower dental caries experience than their immunocompetent counterparts.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibody Formation
  • Bacteria / cytology*
  • Bacteria / immunology
  • Candida / cytology
  • DMF Index
  • Dental Plaque / microbiology*
  • Humans
  • Immunocompetence*
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / microbiology*
  • Lymphocytes / immunology
  • Staphylococcus / cytology