Renal angiomyolipoma associated with lymph node involvement and renal cell carcinoma in patients with tuberous sclerosis

J Urol. 1989 Apr;141(4):930-2. doi: 10.1016/s0022-5347(17)41057-3.


Renal angiomyolipomas are found in more than half of the patients with tuberous sclerosis. We report on 3 patients with tuberous sclerosis and pathologically aggressive renal angiomyolipoma with retroperitoneal lymph node involvement and/or renal cell carcinoma. All patients have had a benign course. The literature is reviewed and supports the benign nature of this seemingly aggressive disorder. An approach to the evaluation and treatment of a child with tuberous sclerosis and renal angiomyolipoma is presented.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Carcinoma, Renal Cell / complications*
  • Child
  • Female
  • Hemangioma / complications*
  • Humans
  • Kidney Neoplasms / complications*
  • Lipoma / complications*
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Male
  • Neoplasms, Multiple Primary / pathology*
  • Tuberous Sclerosis / complications*