Managing opioid overdose in pregnancy with take-home naloxone

Aust N Z J Obstet Gynaecol. 2018 Aug;58(4):460-462. doi: 10.1111/ajo.12761. Epub 2017 Dec 22.

Abstract

Programs have recently been established in Australia and internationally to allow wider access to naloxone to people at risk of opioid overdose yet there are no guidelines relating to the administration of naloxone to pregnant women, particularly regarding dose requirements and resuscitative measures peculiar to pregnancy. This paper provides practical guidelines to health workers in relation to any complications that may arise during opioid overdose response (including the administration of naloxone) for pregnant women and the follow up required ensuring best possible outcomes for mother and baby.

Keywords: naloxone; opioids; overdose; pregnancy; resuscitation.

MeSH terms

  • Analgesics, Opioid / adverse effects*
  • Australia
  • Drug Overdose / prevention & control*
  • Female
  • Humans
  • Injections, Intramuscular
  • Naloxone / administration & dosage
  • Naloxone / therapeutic use*
  • Narcotic Antagonists / administration & dosage
  • Narcotic Antagonists / therapeutic use*
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications / prevention & control*
  • Self Care*

Substances

  • Analgesics, Opioid
  • Narcotic Antagonists
  • Naloxone