Emerging Unconventional Therapies for Alopecia Areata

J Investig Dermatol Symp Proc. 2018 Jan;19(1):S32-S33. doi: 10.1016/j.jisp.2017.10.012.


Alopecia areata is a prevalent autoimmune skin disease with no cure or indicated treatment options. In the absence of an approved treatment, some patients are eager to try unconventional therapies, despite the very limited research evaluating their safety and efficacy. Recently emerging unconventional therapies for alopecia areata discussed include antihistamines, cryotherapy, and low-dose naltrexone.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alopecia Areata / therapy*
  • Autoimmune Diseases / therapy
  • Cryotherapy
  • Histamine Antagonists / therapeutic use
  • Humans
  • Naltrexone / administration & dosage
  • Narcotic Antagonists / administration & dosage


  • Histamine Antagonists
  • Narcotic Antagonists
  • Naltrexone