Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscape

Ann Allergy Asthma Immunol. 2018 Jan;120(1):10-22.e2. doi: 10.1016/j.anai.2017.10.039.


The implementation of treatment guidelines for atopic dermatitis is challenging, in part because of different guidance documents being used by different groups of specialists and in part because the language of guidelines often reflects the evidence base rather than the practical "how to." The Atopic Dermatitis Yardstick is part of a series developed in response to the need to proactively address the loss of disease control for atopic illnesses at all levels of severity. It presents a comprehensive update on how to conduct a sustained step-up in therapy for the patient with inadequately controlled or poorly controlled atopic dermatitis. Patient profiles, based on current guidelines and the authors' combined clinical experience, provide a practical and clinically meaningful guide to aid physicians in helping their patients achieve the goal of clear to almost clear. The intent is not to replace guidelines but to complement their recommendations incorporating the latest research and therapies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Algorithms
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Boron Compounds / therapeutic use*
  • Bridged Bicyclo Compounds, Heterocyclic / therapeutic use*
  • Child
  • Clinical Decision-Making
  • Cyclic Nucleotide Phosphodiesterases, Type 4 / metabolism
  • Dermatitis, Atopic / therapy*
  • Emollients / therapeutic use*
  • Evidence-Based Medicine
  • Humans
  • Phototherapy
  • Practice Guidelines as Topic
  • Quality of Life
  • Research Design


  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Boron Compounds
  • Bridged Bicyclo Compounds, Heterocyclic
  • Emollients
  • dupilumab
  • Cyclic Nucleotide Phosphodiesterases, Type 4
  • PDE4A protein, human
  • crisaborole