ESPEN guideline clinical nutrition in neurology

Clin Nutr. 2018 Feb;37(1):354-396. doi: 10.1016/j.clnu.2017.09.003. Epub 2017 Sep 22.


Neurological diseases are frequently associated with swallowing disorders and malnutrition. Moreover, patients with neurological diseases are at increased risk of micronutrient deficiency and dehydration. On the other hand, nutritional factors may be involved in the pathogenesis of neurological diseases. Multiple causes for the development of malnutrition in patients with neurological diseases are known including oropharyngeal dysphagia, impaired consciousness, perception deficits, cognitive dysfunction, and increased needs. The present evidence- and consensus-based guideline addresses clinical questions on best medical nutrition therapy in patients with neurological diseases. Among them, management of oropharyngeal dysphagia plays a pivotal role. The guideline has been written by a multidisciplinary team and offers 88 recommendations for use in clinical practice for amyotrophic lateral sclerosis, Parkinson's disease, stroke and multiple sclerosis.

Keywords: Amyotrophic lateral sclerosis; Multiple sclerosis; Oropharyngeal dysphagia; Parkinson's disease; Stroke.

Publication types

  • Practice Guideline
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Deglutition Disorders / diagnosis
  • Deglutition Disorders / diet therapy
  • Deglutition Disorders / physiopathology
  • Humans
  • Nervous System Diseases* / diagnosis
  • Nervous System Diseases* / diet therapy
  • Nervous System Diseases* / physiopathology
  • Nutrition Policy*
  • Nutritional Status
  • Prognosis
  • Stroke / diagnosis
  • Stroke / diet therapy
  • Stroke / physiopathology