[Prevalence of Markers of Chronic Kidney Disease in Patients With Arterial Hypertension: Results of Epidemiological Study CHRONOGRAF]

Kardiologiia. 2017 Oct;57(10):39-44. doi: 10.18087/cardio.2017.10.10041.
[Article in Russian]

Abstract

In an noninterventional observational open multicenter program CHRONOGRAF the prevalence of markers of chronic kidney disease (CKD) was studied in 1600 patients with arterial hypertension with and without type 2 diabetes mellitus. Glomerular filtration rate (GFR) was calculated (CKD‑EPI formula) and albuminuria (AU) was determined as albumin/creatinine (A/Cr) ratio in the morning portion of urine. In 49.4% of patients decreased GFR 30 mg/g was detected. Decrease of GFR 30 mg/g - in 32.6%, combination of reduced GFR and high/very high AU - in 18%. High or very high level of combined risk of progression to CKD and cardiovascular complications had 28.5% of patients.

Keywords: albuminuria; arterial hypertension; chronic kidney disease; diabetes mellitus; glomerular filtration rate.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Creatinine
  • Diabetes Mellitus, Type 2*
  • Epidemiologic Studies
  • Glomerular Filtration Rate
  • Humans
  • Hypertension* / complications
  • Prevalence
  • Renal Insufficiency, Chronic* / complications
  • Renal Insufficiency, Chronic* / epidemiology
  • Risk Factors

Substances

  • Creatinine