An update of the evidence on the potential impact of periodontal therapy on diabetes outcomes

J Clin Periodontol. 2018 Feb;45(2):188-195. doi: 10.1111/jcpe.12836. Epub 2017 Dec 26.

Abstract

Aim: To provide an update of the systematic review by Engebretson and Kocher J Clin Periodontol. 2013 Apr;40 Suppl 14:S153 on the effect of periodontal therapy on glycaemic control of people with diabetes.

Methods: PubMed Literature search restricted to meta-analyses published from 2013 to the present was conducted. The search resulted in seven meta-analyses of RCTs.

Results: Reduction in HbA1c at 3-4 months was reported in all reviews for the treatment group ranging from -0.27% (95% CI: -0.46, -0.07, p = .007) to -1.03% (95% CI: 0.36, -1.70, p = 0.003). At 6 months post-treatment, an HbA1c reduction ranging from -0.02 (95% CI: -0.20, -0.16, p = .84) to -1.18% (95% CI: 0.72%, 1.64%, p < 0.001) was reported.

Clinical relevance: The magnitude of the reduction in HbA1c, which is found to be associated with non-surgical periodontal treatment in patients with diabetes, seems to have clinically significant effects on systemic health, and thus should have a place in the treatment of diabetic patients.

Conclusions: Periodontal treatment (SRP) results in a statistically significant reduction in HbA1C levels at 3 months, with a lower reduction at 6 months.

Keywords: HbA1c; glycaemic control; periodontal therapy.

Publication types

  • Review

MeSH terms

  • Blood Glucose / analysis
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / etiology
  • Diabetes Mellitus / therapy
  • Glycated Hemoglobin / analysis
  • Humans
  • Periodontal Diseases / complications
  • Periodontal Diseases / therapy*
  • Treatment Outcome

Substances

  • Blood Glucose
  • Glycated Hemoglobin
  • hemoglobin A1c protein, human