Down syndrome and pediatric obstructive sleep apnea surgery: A national cohort

Laryngoscope. 2018 Aug;128(8):1963-1969. doi: 10.1002/lary.27063. Epub 2017 Dec 27.

Abstract

Objectives/hypothesis: To analyze the trend of sleep surgeries in pediatric patients with Down syndrome (DS) and obstructive sleep apnea (OSA), and to compare this to nonsyndromic (NS) children with OSA.

Study design: Retrospective cohort database analysis.

Methods: Analysis of the 1997 to 2012 editions of the Kid's Inpatient Database was conducted. Using International Classification of Diseases, Ninth Revision codes, all patients with OSA were identified, and subsequently, subgroups of NS children and children with DS were identified. Trends of the number and types of sleep surgeries were analyzed.

Results: A total of 48,301 and 2,991 sleep surgeries were identified in the NS and DS groups, respectively, during the study period. Tonsillectomy with adenoidectomy was the most common procedure in both groups, but the proportion of tonsillectomy with adenoidectomy decreased over time (P < .01). The proportion of palatal surgery and tracheostomy also decreased significantly, whereas there was an increase in the proportion of lingual tonsillectomies, tongue-base reduction procedures, and supraglottoplasties performed in both groups over time. The relative rates of change in these procedures were higher in the DS population.

Conclusions: Tonsillectomy with adenoidectomy remains the most commonly performed procedure, although there was a significant increase in other sleep surgeries performed (lingual tonsillectomy, tongue-base reduction, and supraglottoplasty) between the two study periods, especially in children with DS.

Level of evidence: 2c. Laryngoscope, 1963-1969, 2018.

Keywords: Down syndrome; Kids’ Inpatient Database; Pediatric; obstructive sleep apnea; sleep procedures; sleep-disordered breathing; surgical trends.

MeSH terms

  • Adenoidectomy
  • Adolescent
  • Child
  • Child, Preschool
  • Down Syndrome / complications*
  • Female
  • Humans
  • Infant
  • Male
  • Palate / surgery
  • Retrospective Studies
  • Sleep Apnea, Obstructive / etiology*
  • Sleep Apnea, Obstructive / surgery*
  • Tongue / surgery
  • Tonsillectomy
  • Tracheostomy
  • Young Adult