Peri-implant squamous cell carcinoma

Aust Dent J. 2018 Jun;63(2):261-264. doi: 10.1111/adj.12581. Epub 2018 Feb 1.

Abstract

Peri-implant squamous cell carcinoma is an uncommon pathological manifestation, whereas peri-implantitis is commonly found in association with dental implants. Both present similarly with loss of supporting soft and hard tissue around dental implants; therefore, a careful differential diagnosis is required. The present case concerns a 62-year-old Japanese man who had a dental implant which had been in the left maxillary incisor region for 4 years who apparently developed peri-implantitis. This did not respond to localized therapy and antibiotics so was referred for specialist surgical management. A biopsy confirmed it to be a squamous cell carcinoma rather than an inflammatory lesion. A literature review shows that this is an unusual presentation without a previous history of malignancy, mucosal disease or risk factors for cancers. Although rare, the possibility of peri-implant squamous cell carcinoma should be borne in mind by all practitioners who monitor implant patients.

Keywords: Dental implant; maxillary incisor; peri-implantitis; risk factor; squamous cell carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy
  • Carcinoma, Squamous Cell / etiology*
  • Dental Implants / adverse effects*
  • Humans
  • Inflammation
  • Japan
  • Male
  • Middle Aged
  • Mouth Neoplasms / etiology*
  • Peri-Implantitis / diagnosis*
  • Risk Factors

Substances

  • Dental Implants