Bilateral disciform keratitis of presumed adenoviral etiology

Indian J Ophthalmol. 2018 Jan;66(1):132-134. doi: 10.4103/ijo.IJO_688_17.


Adenoviral conjunctivitis may lead to subepithelial corneal infiltrates as a late complication. Herein, we aim to present a 19-year-old healthy female, who developed bilateral disciform keratitis three weeks after suffering adenoviral conjunctivitis. She presented with widespread subepithelial corneal infiltrates in addition to central corneal edema with white distinct border resembling immune stromal ring, as well as Descemet's folds and keratic precipitates in the central area. Following topical corticosteroid and ganciclovir for 10 days, her condition improved. After 1 month, she had another episode. Short-term topical corticosteroids in addition to long-term topical cyclosporine and nonpreserved artificial tears were able to prevent further recurrences.

Publication types

  • Case Reports

MeSH terms

  • Adenoviridae / genetics
  • Adenovirus Infections, Human / diagnosis*
  • Adenovirus Infections, Human / virology
  • Aqueous Humor / diagnostic imaging
  • Aqueous Humor / virology
  • Conjunctivitis, Viral / complications*
  • Conjunctivitis, Viral / diagnosis
  • DNA, Viral / analysis
  • Diagnosis, Differential
  • Eye Infections, Viral / diagnosis*
  • Eye Infections, Viral / virology
  • Female
  • Humans
  • Keratitis / diagnosis
  • Keratitis / etiology*
  • Keratitis / virology
  • Polymerase Chain Reaction
  • Slit Lamp Microscopy
  • Tomography, Optical Coherence
  • Young Adult


  • DNA, Viral