Bioaccessibility of four calcium sources in different whey-based dairy matrices assessed by in vitro digestion

Food Chem. 2018 Apr 15:245:454-462. doi: 10.1016/j.foodchem.2017.10.108. Epub 2017 Oct 21.

Abstract

Numerous calcium sources are available to enrich food, but their behavior during digestion is still unknown. This study focused on the influence of the gastro-intestinal pH, the food structure and the calcium source on the bioaccessibility of the nutrient. Four calcium sources were studied: calcium carbonate, calcium citrate malate, calcium phosphate and calcium bisglycinate. These were added to dairy matrices, containing cream and whey proteins, of different forms (liquid or gel). The kinetics of solubility and ionic calcium concentration during in vitro digestion were studied, as function of gastro-intestinal pH. All calcium sources were almost fully soluble in the gastric compartment, and then became insoluble in the intestinal phase. The level of calcium insolubilisation in the intestinal phase was not significantly influenced by the matrix structure (liquid or gel), but was more dependent on the calcium source, this effect leading to different final calcium bioaccessibility from 36% to 20%.

Keywords: Bioaccessibility; Calcium; Dairy product; Digestion in vitro; Solubility; Whey protein gel; pH.

MeSH terms

  • Calcium, Dietary / metabolism*
  • Dairy Products / analysis*
  • Digestion*
  • Gastric Mucosa / metabolism*
  • Humans
  • Solubility
  • Whey / chemistry*

Substances

  • Calcium, Dietary