Sialendoscopy in treatment of adult chronic recurrent parotitis without sialolithiasis

Eur Arch Otorhinolaryngol. 2018 Mar;275(3):775-781. doi: 10.1007/s00405-017-4854-7. Epub 2017 Dec 30.

Abstract

Objective: The aim of this prospective study was to evaluate the efficacy of sialendoscopy in the management of adult chronic recurrent parotitis without sialolithiasis. In addition, preliminary results of an initial randomized placebo-controlled trial of single-dose intraductal steroid injection given concurrently with sialendoscopy, are presented.

Methods: Forty-nine adult patients with chronic recurrent parotitis without sialoliths were included in this study. They underwent sialendoscopy and were randomized to receive either a concurrent intraductal injection of isotonic saline solution or 125 mg of hydrocortisone. Symptom severity was evaluated with visual analogue scale (VAS) and by recording symptom frequency and course with a multiple-choice questionnaire completed preoperatively and at 3, 6, and 12 months after the procedure.

Results: The mean VAS score was 5.6 preoperatively and dropped to 2.9 at 3 months, 3.0 at 6 months, and 2.7 at 12 months after the procedure. The VAS score and the frequency of symptoms were significantly lower at 3 (p < 0.001), 6 (p < 0.001) and 12 (p < 0.001) months after the procedure when compared with the preoperative scores indicating that sialendoscopy reduces the symptoms of recurrent parotitis. However, complete permanent resolution of symptoms was rare. Single-dose steroid injection concomitant to sialendoscopy provided no additional benefit, but the current study is not sufficiently powered to determine a clinical difference between the steroid and non-steroid groups.

Conlusion: Sialendoscopy appears to reduce the symptoms of chronic recurrent parotitis. While total permanent symptom remission is rare, sialendoscopy can be considered a safe and relatively efficacious treatment method for this patient group.

Keywords: Chronic recurrent parotitis; Sialadenitis; Sialendoscopy; Steroids.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anti-Inflammatory Agents / therapeutic use*
  • Chronic Disease
  • Combined Modality Therapy
  • Double-Blind Method
  • Endoscopy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Hydrocortisone / therapeutic use*
  • Male
  • Middle Aged
  • Parotitis / diagnosis
  • Parotitis / therapy*
  • Prospective Studies
  • Salivary Gland Calculi
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Hydrocortisone