Non-interventional 1-year follow-up study of peri-implant soft tissues following previous soft tissue augmentation and crown insertion in single-tooth gaps

J Clin Periodontol. 2018 Apr;45(4):504-512. doi: 10.1111/jcpe.12865. Epub 2018 Feb 1.


Aim: To assess peri-implant soft tissue dimensions at implant sites, previously augmented with a collagen matrix (VCMX) or an autogenous subepithelial connective tissue graft (SCTG), between crown insertion and 1 year.

Methods: Twenty patients with single-tooth implants received soft tissue augmentation prior to abutment connection randomly using VCMX or SCTG. Following abutment connection 3 months later, final reconstructions were fabricated and inserted (baseline). Patients were recalled at 6 months (6M) and at 1 year (FU-1). Measurements included clinical data, soft tissue thickness, volumetric outcomes and patient-reported outcome measures (PROMs).

Results: The buccal soft tissue thickness showed a median decrease of -0.5 mm (-1.0;0.3) (VCMX) and 0.0 mm (-0.5;1.0) (SCTG) (p = .243) up to FU-1. The soft tissue volume demonstrated a median decrease between BL and FU-1 of -0.1 mm (-0.2;0.0) (p = .301) for VCMX and a significant decrease of -0.2 mm (-0.4; -0.1) (p = .002) for SCTG, respectively. Intergroup comparisons did not reveal any significant differences between the groups for peri-implant soft tissue dimensions and changes up to FU-1 (p > .05). PROMs did not show any significant changes over time nor differences between the groups.

Conclusion: Between crown insertion and 1 year, the buccal peri-implant soft tissue dimensions remained stable without relevant differences between sites that had previously been grafted with VCMX or SCTG.

Keywords: 1-year follow-up; collagen-based matrix; dental implant; soft tissue augmentation; soft tissue volume; subepithelial connective tissue graft.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Collagen*
  • Connective Tissue / transplantation*
  • Crowns*
  • Dental Implantation, Endosseous
  • Dental Implants, Single-Tooth*
  • Female
  • Follow-Up Studies
  • Guided Tissue Regeneration, Periodontal / methods*
  • Humans
  • Male
  • Middle Aged
  • Mouth Mucosa / anatomy & histology*


  • Collagen