Comparing Different Adverse Effects Among Multiple Drugs Using FAERS Data

Stud Health Technol Inform. 2017;245:1268.

Abstract

US Food and Drug Administration (FDA) Adverse Event (AE) Reporting System (FAERS) is a major source of data for monitoring drug safety. However, there is not general procedure to systematically compare drugs group. We present a statistical method, which can effectively identify significant differences in AE rates among drugs and estimates the differences in age and gender distributions.

Keywords: Adverse Drug Reaction Reporting Systems; Data Mining.

MeSH terms

  • Adolescent
  • Adult
  • Adverse Drug Reaction Reporting Systems*
  • Age Factors
  • Aged
  • Child
  • Data Interpretation, Statistical
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pharmaceutical Preparations
  • Sex Factors
  • United States
  • United States Food and Drug Administration*
  • Young Adult

Substances

  • Pharmaceutical Preparations