Overexpression of RUNX1 short isoform has an important role in the development of myelodysplastic/myeloproliferative neoplasms

Blood Adv. 2017 Jul 31;1(18):1382-1386. doi: 10.1182/bloodadvances.2016002725. eCollection 2017 Aug 8.


RUNX1a, but not RUNX1b, is overexpressed in CD34+ cells from patients with myelodysplastic/myeloproliferative neoplasms.SRSF2P95H mutation induces RUNX1a overexpression and a monocytic phenotype in TF-1 cells.