A new method of analgesia for relief of circumcision pain

Anaesthesia. 1989 Feb;44(2):118-20. doi: 10.1111/j.1365-2044.1989.tb11158.x.

Abstract

A prospective, randomised, double-blind study was designed to determine whether topical application of 2% lignocaine is effective in decreasing analgesic drug requirements during and after circumcision surgery. General anaesthesia with halothane and nitrous oxide 60-70% in oxygen was administered via a facemask and a Bain system. Administration of halothane was stopped after removal of the foreskin; lignocaine (2%) or placebo was applied topically as drops to the surface of the penis to two groups of patients. Halothane was restarted if the anaesthesia was ineffective. The intra-operative consumption of halothane was significantly less (p less than 0.05) in the treated group as compared with the placebo group (0 and 17, SEM 3, % x minute). The treated group required significantly less (p less than 0.002) pethidine after operation (5 and 10 patients), and the pain-free period was significantly longer (p less than 0.01) (41, SEM 6 and 6, SEM 2 minutes) as compared with the placebo group.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Anesthesia, General
  • Child
  • Child, Preschool
  • Circumcision, Male*
  • Double-Blind Method
  • Halothane
  • Humans
  • Infant
  • Intraoperative Period
  • Lidocaine / administration & dosage*
  • Male
  • Nitrous Oxide
  • Pain, Postoperative / prevention & control*
  • Prospective Studies
  • Random Allocation

Substances

  • Lidocaine
  • Nitrous Oxide
  • Halothane