Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):349-358. doi: 10.1016/j.bbalip.2018.01.001. Epub 2018 Jan 3.
No abstract available

Keywords: Annexin A8; Cholesterol; Cooperativity; Endolysosome; Niemann Pick; Quartz crystal microbalance with dissipation; Solid-supported lipid bilayers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Annexins / metabolism*
  • Calcium / metabolism
  • Carrier Proteins / metabolism
  • Cholesterol / metabolism*
  • Cholesterol, LDL / metabolism
  • Endosomes / metabolism
  • HeLa Cells
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Lipid Bilayers / metabolism*
  • Lysosomes / metabolism
  • Membrane Glycoproteins / metabolism
  • Membranes, Artificial
  • Niemann-Pick C1 Protein
  • Phosphatidylserines / metabolism
  • Protein Binding

Substances

  • Annexins
  • Carrier Proteins
  • Cholesterol, LDL
  • Intracellular Signaling Peptides and Proteins
  • Lipid Bilayers
  • Membrane Glycoproteins
  • Membranes, Artificial
  • NPC1 protein, human
  • Niemann-Pick C1 Protein
  • Phosphatidylserines
  • 1-palmitoyl-2-oleoylglycero-3-phosphoserine
  • Cholesterol
  • Calcium